Acne is one of the more common side effects of testosterone replacement therapy (TRT). As hormone levels shift, the skin’s oil glands become more active, often leading to clogged pores and inflammation. For men starting TRT in India, understanding this connection can help manage breakouts effectively.
At Nova Men’s Health, we often get questions from patients about skin changes after starting TRT. Testosterone plays a key role in skin health—but when levels are artificially boosted, it can throw your skin off balance. Here’s what’s happening under the surface.
1. More Oil = More Acne
Testosterone, especially in its stronger form called DHT (dihydrotestosterone), triggers sebaceous glands to produce more oil or sebum. While sebum protects the skin, excess amounts can clog pores—creating the ideal environment for acne.
2. Hormonal Fluctuations
When TRT begins, hormone levels don’t adjust smoothly. There’s often a temporary spike in testosterone and DHT levels, especially in men with genetically sensitive skin. This makes the skin more reactive and prone to breakouts.
3. Bacterial Overgrowth and Inflammation
Acne-causing bacteria, like Cutibacterium acnes, thrive in oily, clogged pores. As oil builds up, these bacteria multiply and cause inflammation, resulting in red, swollen pimples or even cystic acne.
4. Dead Skin Cell Buildup
TRT may also affect how fast your skin sheds dead cells. When old cells don’t clear properly, they mix with oil and clog the pores further. This adds another layer to the acne problem, especially for men with a history of breakouts.
How to Control Acne While on TRT
1. Gentle Skincare: Use mild cleansers and non-comedogenic products that won’t block pores.
2. Targeted Treatments: Products with salicylic acid, benzoyl peroxide, or retinoids can reduce oil and bacteria.
3. Adjust TRT Protocol: Sometimes, switching the dose or delivery method (injection, gel, or patch) helps.
4. Diet Matters: Cut down on dairy and high-sugar foods. Drink more water.
5. Prescription Help: If acne gets severe, a doctor might suggest antibiotics or other medications like isotretinoin.
Your body is adjusting on testosterone
Acne doesn’t mean TRT isn’t working—it just means your body is adjusting. At Nova Men’s Health, we help men across India find hormone balance without sacrificing skin health. With the right approach, it’s possible to enjoy the benefits of TRT and keep acne under control.